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41 results

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Page 1
Vector-related stratagems for enhanced monoclonal antibody production in mammalian cells.
Gupta K, Parasnis M, Jain R, Dandekar P. Gupta K, et al. Biotechnol Adv. 2019 Dec;37(8):107415. doi: 10.1016/j.biotechadv.2019.107415. Epub 2019 Jul 3. Biotechnol Adv. 2019. PMID: 31279066 Review.
Further, the components of the vector need to be optimized via genetic engineering approaches, to exclude non-productive clones, reduce low secretion levels, eliminate improper functioning that affect mAb heavy chain and light chain ratio, glycosylation and aggregat …
Further, the components of the vector need to be optimized via genetic engineering approaches, to exclude non-productive clone …
Topical drug delivery in the eye.
Wilson CG. Wilson CG. Exp Eye Res. 2004 Mar;78(3):737-43. doi: 10.1016/j.exer.2003.10.004. Exp Eye Res. 2004. PMID: 15106953 Review.
Introduction of a drug or polymer directly into the conjunctival sac should, in theory, facilitate the maximum level of efficacy. In practice, most material undergoes non-productive loss. The work of David Maurice facilitated a better understanding of drug entry by …
Introduction of a drug or polymer directly into the conjunctival sac should, in theory, facilitate the maximum level of efficacy. In practic …
Construction of Mycoplasma hyopneumoniae P97 Null Mutants.
Clampitt JM, Madsen ML, Minion FC. Clampitt JM, et al. Front Microbiol. 2021 Apr 22;12:518791. doi: 10.3389/fmicb.2021.518791. eCollection 2021. Front Microbiol. 2021. PMID: 33967967 Free PMC article.
Mycoplasma hyopneumoniae is the causative agent of enzootic pneumonia, a world-wide problem in the pig industry. This disease is characterized by a dry, non-productive cough, labored breathing, and pneumonia. Despite years of research, vaccines are marginally effect …
Mycoplasma hyopneumoniae is the causative agent of enzootic pneumonia, a world-wide problem in the pig industry. This disease is characteriz …
Characterization of productive and non-productive AcMNPV infection in selected insect cell lines.
Morris TD, Miller LK. Morris TD, et al. Virology. 1993 Nov;197(1):339-48. doi: 10.1006/viro.1993.1595. Virology. 1993. PMID: 8212569
We have investigated the process of productive and non-productive AcMNPV infection in a variety of cultured insect cells including lines derived from Spodoptera frugiperda (IPLB-SF21), Mamestra brassicae (SES-MaBr-3), Choristoneura fumiferana (IPRL-CF-1), Bombyx mor …
We have investigated the process of productive and non-productive AcMNPV infection in a variety of cultured insect cells inclu …
Discrimination between transfer-RNAs by tyrosyl-tRNA synthetase.
Bedouelle H, Guez-Ivanier V, Nageotte R. Bedouelle H, et al. Biochimie. 1993;75(12):1099-108. doi: 10.1016/0300-9084(93)90009-h. Biochimie. 1993. PMID: 8199245 Review.
We have constructed a model of the complex between tyrosyl-tRNA synthetase (TyrRS) from Bacillus stearothermophilus and tRNA(Tyr) by successive cycles of predictions, mutagenesis of TyrRS and molecular modeling. ...The overproductions of the wild type TyrRSs from E coli an …
We have constructed a model of the complex between tyrosyl-tRNA synthetase (TyrRS) from Bacillus stearothermophilus and tRNA(Tyr) by …
Split luciferase-based biosensors for characterizing EED binders.
Li L, Feng L, Shi M, Zeng J, Chen Z, Zhong L, Huang L, Guo W, Huang Y, Qi W, Lu C, Li E, Zhao K, Gu J. Li L, et al. Anal Biochem. 2017 Apr 1;522:37-45. doi: 10.1016/j.ab.2017.01.014. Epub 2017 Jan 19. Anal Biochem. 2017. PMID: 28111304
Based on the crystal structure, the DSF data as well as the biosensor assay data, it's most likely that compound-induced increase in the luciferase activity of the EED[G255D] biosensor results from the decreased non-productive interactions between the EED subdomain …
Based on the crystal structure, the DSF data as well as the biosensor assay data, it's most likely that compound-induced increase in the luc …
The avian B-cell receptor complex: distinct roles of Igalpha and Igbeta in B-cell development.
Pike KA, Baig E, Ratcliffe MJ. Pike KA, et al. Immunol Rev. 2004 Feb;197:10-25. doi: 10.1111/j.0105-2896.2004.0111.x. Immunol Rev. 2004. PMID: 14962183 Review.
B-cell precursors that express an sIg complex that includes the evolutionarily conserved Igalpha/beta heterodimer colonize lymphoid follicles in the bursa, whereas B-cell precursors that fail to express sIg due to non-productive V(D)J recombination are eliminated. P …
B-cell precursors that express an sIg complex that includes the evolutionarily conserved Igalpha/beta heterodimer colonize lymphoid follicle …
Supercharging carbohydrate-binding module alone enhances endocellulase thermostability, binding, and activity on cellulosic biomass.
DeChellis A, Nemmaru B, Sammond D, Douglass J, Patil N, Reste O, Chundawat SPS. DeChellis A, et al. bioRxiv [Preprint]. 2023 Sep 12:2023.09.09.557007. doi: 10.1101/2023.09.09.557007. bioRxiv. 2023. PMID: 37745483 Free PMC article. Preprint.
Lignocellulosic biomass recalcitrance to enzymatic degradation necessitates high enzyme loadings incurring large processing costs for industrial-scale biofuels or biochemicals production. Manipulating surface charge interactions to minimize non-productive interactio …
Lignocellulosic biomass recalcitrance to enzymatic degradation necessitates high enzyme loadings incurring large processing costs for indust …
The role of glycosylation in non-productive adsorption of cellulase to lignin isolated from pretreated corn stover.
Zhang Y, Li H, Xin Q, Zhao J, Xia T, Lu X. Zhang Y, et al. Int J Biol Macromol. 2024 May;266(Pt 1):130836. doi: 10.1016/j.ijbiomac.2024.130836. Epub 2024 Mar 16. Int J Biol Macromol. 2024. PMID: 38492700
Additionally, N-glycan sites and motifs were examined using mass spectrometry, and protein structures with N-glycans were constructed, where PoBgl1 and PoCel7A-2 contained 13 and 1 glycosylated sites respectively. ...
Additionally, N-glycan sites and motifs were examined using mass spectrometry, and protein structures with N-glycans were constructed …
Identifying causes of the 2015 Hopa flash flood in NE Turkey and mitigation strategies.
Çelik HE, Kurdoğlu O, İnan M, Kadıoğlu M, Nişancı İ. Çelik HE, et al. Environ Monit Assess. 2020 Nov 19;192(12):769. doi: 10.1007/s10661-020-08737-w. Environ Monit Assess. 2020. PMID: 33215246
In order to control torrents and floods in the Sundura watershed, afforestation is needed for non-productive forest and tea cultivation areas in the upper watershed. In the lower part of the watershed, the main channel should be redesigned according to the Q(500) ye …
In order to control torrents and floods in the Sundura watershed, afforestation is needed for non-productive forest and tea cu …
41 results